Journal: The EMBO Journal

Article Title: The DDHD2-STXBP1 interaction mediates long-term memory via generation of saturated free fatty acids

doi: 10.1038/s44318-024-00030-7

Figure Lengend Snippet: ( A ) Line graphs showing monthly recordings of a motor coordination, assessed using a rotarod device by determining the latency period from when the mouse is placed on the accelerating rotating rod device to the initial fall (s), and ( B ) motor strength (N), assessed using a grip strength device. Longitudinal monitoring of mouse activity with line graphs showing ( C ) vertical counts, ( D ) jump counts, ( E ) ambulatory distance (m), ( F ), vertical time (s), and ( G ) jump time (s). ( H ) Longitudinal assessment of spatial memory performance in mice, using the Novel Object Location (NOL) paradigm, represented as a line graph. Data information: In ( A – H ), the significance of the difference between each group as determined by one-way ANOVA ( n = 20) is indicated by asterisks * p < 0.05, ** p < 0.01, *** p < 0.001, ns = not significant. Error bars represent the cumulative standard error of the mean (SEM) for all groups and parameters.

Article Snippet: Using an automated activity monitoring device (Med Associates), we assessed open-field locomotor performance, alongside explorative and vigilance activity.

Techniques: Activity Assay